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Science News

Location American Science News for 2 April 2019
Liver, colon cancer cells thwarted by compounds derived from hops The plant that adds flavor, color and bitterness to beer also produces a primary compound that thwarts cancer cells, and two important derivatives of the compound do as well.
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Is your melanoma hot enough for immunotherapy?

Science Daily - 2 Apr 2019 22:45
A new study shows that tumors with mutations in genes leading to over-activation of the NF-kB signaling pathway were more than three times as likely to respond to anti-PD1 immunotherapy compared with tumors in which thes...
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A student has shown that surgery is associated with higher survival rates for patients with HER2-positive stage 4 breast cancer compared with those who did not undergo surgery. The protein HER2, or human epidermal growth...
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Study debunks 'depression genes' hypotheses

Science Daily - 2 Apr 2019 22:45
A new study assessing data from 620,000 individuals found that the 18 most highly-studied candidate genes for depression are no more associated with depression than randomly chosen genes.
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Potential fix for hospital star rating program

Science Daily - 2 Apr 2019 22:45
Allowing for more quality measures in the federal government's Quality Star Rating program would create a fairer and more equitable model for assessing the level of quality at US acute-care hospitals, according to a new ...
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The difficulty in spotting minute amounts of disease circulating in the bloodstream has proven a stumbling block in the detection and treatment of cancers that advance stealthily with few symptoms. With a novel electroch...
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Efforts to curtail the flow of cocaine into the United States from South America have made drug trafficking operations more widespread and harder to eradicate.
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New role for a driver of metastatic cancers

Science Daily - 2 Apr 2019 22:44
New role for a driver of metastatic cancers Metastatic ovarian, prostate and breast cancers are notoriously difficult to treat and often deadly. Now, researchers have revealed a new role for the CDK12 protein.
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MW-151, a new drug that blocks 'bad' inflammation in the brain is about to be tested in a new human trial. Researchers believe the new drug could help stave off dementia.
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Parasitology: Exotic signaling mechanism in pathogens The unicellular parasite that causes sleeping sickness differs from other eukaryotes in the mode of regulation of an essential cellular signaling pathway. This provides a promising point of attack for drug development.
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Until now, no large study has evaluated whether or not caring for older adults with advanced cancer is linked to caregivers' emotional health or to their quality of life. Recently, researchers studied a group of adults a...
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3D-printed transparent skull provides a window to the brain Researchers have developed a unique 3D-printed transparent skull implant for mice that provides an opportunity to watch activity of the entire brain surface in real time. The device allows fundamental brain research that...
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A large genomic study of nearly 275,000 people has revealed new insights into genetic drivers of heavy drinking and alcohol use disorder (AUD), the uncontrollable pattern of alcohol use commonly referred to as alcoholism...
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Researchers induced jet lag in a fruit fly model of Huntington disease and found that jet lag protected the flies' neurons.
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More than 113 million people across 53 countries experienced acute hunger requiring urgent food, nutrition and livelihoods assistance in 2018, according to a new report.
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Particle beam therapy, a form of radiotherapy that involves using beams of positively charged particles rather than X-rays, is becoming increasingly popular. Treatment plans need to be optimized so as to maximize irradia...
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High throughput method to produce and screen engineered antimicrobial lanthipeptides Nature has provided us with lots of antimicrobials. However, given the rapid increase of antimicrobial resistance, there is a need for the development of new-to-nature antibiotics. Lantibiotics are an interesting option....
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Mammography remains an effective method for breast cancer screening in women ages 65 and older, with the addition of a 3D technique called tomosynthesis improving screening performances even more, according to a new stud...
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Bariatric embolization, a new, minimally invasive treatment for obesity produces weight loss and reduces appetite for up to one year, according to a new study.
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Reproductive spans of less than 34 years were linked to an increased risk of developing dementia in women. In those who had hysterectomies, the associated Alzheimer's risk was elevated by 8%.
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PET imaging that helps detect dementia-related amyloid plaques significantly influences the clinical management of patients, a new study reports.
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18 genetic variants have been identified which appear to be associated with alcohol use disorder and heavy drinking. Of these genes, five were overlapped, eight were associated with heavy consumption and five were linked...
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